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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKY
All Species:
17.58
Human Site:
S99
Identified Species:
32.22
UniProt:
O43930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43930
NP_005035
277
31708
S99
Q
H
V
H
N
E
K
S
V
L
K
E
V
S
H
Chimpanzee
Pan troglodytes
XP_001145269
358
40936
S99
Q
H
V
H
N
E
K
S
V
L
K
E
V
S
H
Rhesus Macaque
Macaca mulatta
XP_001086667
358
40973
S99
Q
H
V
H
N
E
K
S
V
L
K
E
V
S
H
Dog
Lupus familis
XP_852513
341
38934
F91
L
K
E
V
S
H
P
F
L
V
K
L
F
W
T
Cat
Felis silvestris
Mouse
Mus musculus
Q922R0
355
40448
A96
Q
H
V
Q
N
E
K
A
V
L
K
E
I
N
H
Rat
Rattus norvegicus
P68182
351
40689
R94
E
H
T
L
N
E
K
R
I
L
Q
A
V
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514495
450
51108
S191
Q
H
V
H
N
E
K
S
V
L
K
E
V
N
H
Chicken
Gallus gallus
Q6U1I9
432
48872
V150
H
I
M
S
E
R
N
V
L
L
K
N
V
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
V151
H
I
M
S
E
R
N
V
L
L
K
N
V
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16912
583
65389
N324
E
H
V
K
N
E
R
N
I
L
R
E
I
R
H
Honey Bee
Apis mellifera
XP_393711
374
42855
T115
E
H
V
R
N
E
I
T
V
L
K
E
V
N
H
Nematode Worm
Caenorhab. elegans
P21137
404
46327
R131
E
H
T
L
N
E
K
R
I
L
Q
A
I
D
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
R120
E
H
T
N
D
E
R
R
M
L
K
L
V
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
70.9
61.5
N.A.
56.3
37.8
N.A.
49.7
31.2
N.A.
30
N.A.
28.1
42.5
32.9
N.A.
Protein Similarity:
100
74.8
73.7
66.5
N.A.
64.2
54.4
N.A.
55.1
43
N.A.
44.1
N.A.
38.5
54
50.9
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
73.3
40
N.A.
93.3
26.6
N.A.
26.6
N.A.
46.6
66.6
33.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
60
N.A.
100
40
N.A.
40
N.A.
86.6
86.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
39
0
8
0
16
77
0
0
0
0
0
54
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
16
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
16
77
0
31
0
8
0
0
0
0
0
0
0
0
77
% H
% Ile:
0
16
0
0
0
0
8
0
24
0
0
0
24
0
0
% I
% Lys:
0
8
0
8
0
0
54
0
0
0
77
0
0
16
0
% K
% Leu:
8
0
0
16
0
0
0
0
24
93
0
16
0
0
0
% L
% Met:
0
0
16
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
70
0
16
8
0
0
0
16
0
24
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
39
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% Q
% Arg:
0
0
0
8
0
16
16
24
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
16
8
0
0
31
0
0
0
0
0
24
0
% S
% Thr:
0
0
24
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
54
8
0
0
0
16
47
8
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _